The shape of DNA can be changed with a range of triggers including copper and oxygen, according to new research from the University of East Anglia, U.K. The structure of DNA is widely accepted to exist as a double helix, but different DNA structures also exist. The new research points to a range of triggers that can manipulate its shape. Applications for this discovery include nanotechnology (where DNA is used to make tiny machines), and in DNA-based computing (where computers are built from DNA rather than silicon). The paper, “Redox dependent control of i-motif DNA structure using copper cations” has been published in the journal, Nucleic Acids Research.